Changes the Rules Vaccine: Mucosal Route of Administration Prime-Boost Immunization with DNA
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منابع مشابه
Prime-boost immunization with DNA vaccine: mucosal route of administration changes the rules.
In this study we assessed prime-boost immunization strategies with a DNA vaccine (gB DNA) and attenuated recombinant vaccinia virus vector (rvacgB), both encoding the gB protein of HSV, for their effectiveness at inducing mucosal as well as systemic immunity to HSV. Confirming the reports of others, systemic priming with gB DNA and systemic boosting with rvacgB were the most effective means of ...
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